翻訳と辞書 Words near each other ・ Nadalama, Rapla County ・ Nad Niemnem ・ Nad Niemnem (film) ・ Nad Rzeką ・ Nad Shamma ・ Nad Tatrou sa blýska ・ NAD X Road ・ Nad's ・ NAD(+)—dinitrogen-reductase ADP-D-ribosyltransferase ・ NAD(+)—diphthamide ADP-ribosyltransferase ・ NAD(P)(+)—protein-arginine ADP-ribosyltransferase ・ NAD(P)+ nucleosidase ・ NAD(P)+ transhydrogenase ・ NAD(P)+ transhydrogenase (Re/Si-specific) ・ NAD(P)+ transhydrogenase (Si-specific) ・ NAD(P)H dehydrogenase (quinone 1) ・ NAD(P)H dehydrogenase (quinone) ・ NAD(P)H dehydrogenase, quinone 2 ・ NAD(P)H oxidase ・ NAD(P)H-hydrate epimerase ・ NAD+ diphosphatase ・ NAD+ in neurodegeneration ・ NAD+ kinase ・ NAD+ nucleosidase ・ NAD+ pyrophosphorylase ・ NAD+ synthase ・ NAD+ synthase (glutamine-hydrolysing) ・ NAD+ transhydrogenase ・ Nad, County Cork ・ Nada Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク NAD(P)H dehydrogenase (quinone 1) ： ウィキペディア英語版 NAD(P)H dehydrogenase (quinone 1) NAD(P)H dehydrogenase () 1 is an enzyme that in humans is encoded by the ''NQO1'' gene. This protein-coding gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a 2-electron reductase (enzyme). This FAD-binding protein forms homodimers and performs two-electron reduction of quinones to hydroquinones and of other redox dyes. It has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone. This gene has an important paralog NQO2. This protein is located in the cytosol.〔(【引用サイトリンク】url=http://compartments.jensenlab.org/Entity?figures=subcell_cell_%&knowledge=10&textmining=10&experiments=10&predictions=10&type1=9606&type2=-22&id1=ENSP00000319788 )〕 NQO1 enzyme expression can be induced by dioxin and inhibited by dicoumarol. == Function == This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1728 )〕 The ubiquitin-independent p53 degradation pathway is regulated by NQO1. NQO1 stabilizes p53, protecting it from degradation. Individuals with decreased NQO1 expression/activity have reduced p53 stability, which may lead to resistance to drugs such as chemotherapeutics. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「NAD(P)H dehydrogenase (quinone 1)」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.